Type 1 Diabetes and Associated Autoimmune Diseases (Celiac, Autoimmune Thyroid, Vitiligo)
DOI:
https://doi.org/10.64516/v4wa9z93Keywords:
Celiac diseases, Autoimmune Thyroid Diseases, Type 1 Diabetes.Abstract
Diabetes mellitus is a common autoimmune endocrine disorder associated with organ- specific autoantibodies which are frequently detected at the time of diagnosis. Individuals with type 1 diabetes have increased prevalence of other autoimmune diseases including autoimmune thyroid disease, celiac disease, and primary adrenal failure. In some patients, a shared genetic susceptibility for these diseases has been demonstrated. To define the prevalence of autoimmune disease in Libyan patients with type 1 diabetes mellitus (T1DM). Blood samples were collected from 99 patients with T1DM who are followed by Tobruk Diabetic Center, Libya. The patients were composed of 45 females (45.4%) and 54 males (54.5 %), of the diabetic children 10 patients about 10.1% were positive for celiac disease(female 6 %and 4male %) confirm with ant tissue -transglutaminase ( TTG) , patient with diabetes had significant higher incidence of celiac diseases, also In this study we found 4 patients have autoimmune thyroid disease about( 4%) belonged to female sex ,vitiligo 2patients female predominance. From previous result we concluded that the prevalence of autoimmune thyroid diseases, celiac diseases, vitiligo is high in (T1DM) especially among female patients.
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